Role of Intestinal Microflora on Necrotizing Enterocolitis in Preterm Infants
نویسندگان
چکیده
Despite overall decreasedmortality andmorbidity in preterm very low-birth-weight (VLBW:<1,500 g) infants over the past decades, necrotizing enterocolitis (NEC), a devastating emergency intestinal disease in preterm VLBW infants, remains 5 to 6% and even increase despite much effort on peri-postnatal care.1 More worrisome, approximately 20 to 30% of VLBW infants with NECwill die2 and the remaining survivors will be at substantial risk for long-term complications, including impaired neurodevelopment and short bowel syndrome.3 Around 10% of infants with NEC are term or near-term neonates; the risk factors of NEC in term neonates include congenital heart diseases, prenatal asphyxia, and patent
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